Ribavirin

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Alias ribavirin.
Foreign Name ribavirin, ICN-1229, RTC, Tribavirin Viramid, virazol pharmacological and software may impede broad spectrum antiviral inosine monophosphate -5 - phosphate dehydrogenase, blocking inosine monophosphate nucleotides in birds, thus preventing the viral RNA and DNA synthesis and inhibit DNA replication RNA viruses and viruses. For the prevention and treatment of influenza, parainfluenza, A, B, hepatitis C, measles, mumps, chickenpox, herpes simplex, with
Alias ribavirin, ribavirin, ribavirin; Ville Star; Ribavirin, triazole nucleoside; triazole nucleoside; amide-triazine nucleosides.
Foreign names ribavirin, ICN-1229, RTC, Tribavirin, Viramid, virazol

Pharmacological applications for a wide spectrum antiviral drug, can inhibit inosine monophosphate -5 - phosphate dehydrogenase, blocking inosine monophosphate in guanylate, thus inhibiting viral RNA and DNA synthesis, DNA and RNA viruses were inhibited virus replication. For the prevention and treatment of influenza, parainfluenza, A, B, hepatitis C, measles, mumps, chickenpox, herpes simplex, herpes zoster, viral keratitis eye, vesicular stomatitis, pediatric pneumonia adenovirus can be anti-tumor effect.
Internal clinically confirmed at epidemic hemorrhagic fever, especially in the early effectiveness significantly reduce patient mortality, reduce kidney damage and reduce the tendency to bleed, to enhance the role of systemic symptoms.
Consumption of
Oral: 1 day from 0.8 to 1 g, three or four times to take. 2. Intramuscular injection or intravenous infusion: 1 day per kilogram of body weight of 10 ~ 15 mg, 2 times. Infusion should be slow. Intranasal: prevention and treatment of influenza, be formulated with an isotonic saline with 0.5% (), 1:00. 4 drops: the treatment of herpes infections, the concentration of 0.1%, several times in the 1st.
Note 1. 0.5% nasal solution, efficient and reliable, pediatric particularly suitable to start a space should be almost, later changed to a 2:00 time.
Adverse reactions: leukopenia, anemia, diarrhea, dry mouth.
3 large doses can cause damage to the heart, patients with respiratory diseases can cause shortness of breath, chest pain.
Disable: pregnant women (teratogenic).
Specification eye ​​drops: 0.1%. Nose drops: 0.5%. Injections: Each 100 mg (1 mL). Tablet: 0.1g.
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